Jump to content
You are a guest user Click to join the site
  • Sign Up

Welcome Guest

Welcome to drugbuyersguide, like most online communities you must register to view or post in our community, but don't worry this is a simple free process that requires minimal information for you to signup. Be apart of Drug Buyers Guide Forum by signing in or creating an account.

  • Start new topics and reply to others
  • Subscribe to topics and forums to get email updates
  • Get your own profile page and make new friends
  • Send personal messages to other members.

GDAs and insulin sensitivity


EasyMoneySnip3r
 Share

Recommended Posts

  • Grand Poobah
EasyMoneySnip3r

  • Group:  Grand Poobah
  • Topic Count:  332
  • Content Count:  1,126
  • Reputation:   434
  • Joined:  05/02/2021
  • Status:  Offline
  • Last Seen:  

GDA's work well. They help retain insulin sensitivity and partition nutrients. Pretty simple answer.  Does anyone use GDAs

Link to comment
Share on other sites

  • Opal Sponsor

  • Group:  Opal Sponsor
  • Topic Count:  4
  • Content Count:  151
  • Reputation:   85
  • Joined:  05/17/2021
  • Status:  Offline
  • Last Seen:  

@Ayyy7393 All I know about them is that if you're going to take berberine you have to be careful since it inhibits CYP2D6 and CYP3A4 so you shouldn't take it with most... fun stuff. And also antidepressants, beta-blockers, I would just avoid that one.

Link to comment
Share on other sites

  • Grand Poobah
EasyMoneySnip3r

  • Group:  Grand Poobah
  • Topic Count:  332
  • Content Count:  1,126
  • Reputation:   434
  • Joined:  05/02/2021
  • Status:  Offline
  • Last Seen:  

@TommyAC can you elaborate on the anti D and B3ta

ty!!

Link to comment
Share on other sites

  • Opal Sponsor

  • Group:  Opal Sponsor
  • Topic Count:  4
  • Content Count:  151
  • Reputation:   85
  • Joined:  05/17/2021
  • Status:  Offline
  • Last Seen:  

@Ayyy7393 I don't know if we can post links so I'll copy paste the list of affected drugs. Most of these will be metabolized more slowly, making them prone to accumulation, which is very dangerous in some cases. A minority need to be metabolized to be activated so they will have a lesser effect. For example c0de1ne and tr@m@dol won't be metabolized into m0rph1ne and 0-dsmt as much respectively and because of that will have little effect.

CYP2D6

image.thumb.png.d3ce7d7ae51ea409c6fb41cd62d37f2f.png

CYP3A4

image.thumb.png.4e5c793cd6c1a405024ad5f70ebfff9d.png

image.thumb.png.9c188b698a60a1cd1b3ef9bbf3854196.png

The other thing to keep in mind is that unlike some drugs like some SSR1s, we11butrin and some HIV medications, there are very little studies on how much berberine inhibits these 2 enzymes, meaning there could be some deadly combinations in those lists but there's no way of knowing except taking berberine and one of them, which is obciously dangerous.

In my opinion, here's the thing. I take pr1midone for the essential tremor l1thium gives me. Pr1midone is well known to inhibit or induce several enzymes, but because it has been in the market for 50 years we pretty much know if a combination is safe. With berberine you're going into unknown territory and I don't think the risks (OD, liver/kidney failure, death, etc) are worth taking for what's essentially a supplement, specially when you have several alternatives. So I would simply avoid it.

Link to comment
Share on other sites

Join the conversation

You can post now and register later. If you have an account, sign in now to post with your account.

Guest
Reply to this topic...

×   Pasted as rich text.   Paste as plain text instead

  Only 75 emoji are allowed.

×   Your link has been automatically embedded.   Display as a link instead

×   Your previous content has been restored.   Clear editor

×   You cannot paste images directly. Upload or insert images from URL.

 Share

×
×
  • Create New...